Knowledge about protein expression levels is of utmost importance to predict toxic effects, estimate adverse effects of drug candidates and to identify new drug targets. Sciomics has a highly optimised range of protein profiling services available. These help you to speed up your research and generate important data at lower cost through a highly-parallel protein expression level analysis using our Scio-Discover Antibody Microarray Platform. Furthermore, you may link to and verify your Genomics and Transcriptomics data with protein expression levels.
Applications:
- Pre-clinical Toxicology Studies
- rodents such as mice* and rats*
- cell culture models
- tissue culture models
- Drug target identification and verification
- Mechanistic studies for various indications
- Profile cytokine and inflammatory status
- Protein Biomarker identification and verification
Key advantages:
- High multiplexity (more than 1,400 proteins in parallel)
- Low sample consumption
- Investigation of human and murine samples*
- Fast turnaround time, as low as two weeks**
- No need for laborious depletion or fractionation of your samples
- High sensitivity (as sensitive as an ELISA or better)
- High reproducibility (CV < 10%)
- Various sample types can be investigated
- Plasma or Serum
- fresh-frozen tissue samples
- Cell culture samples
- Cerebrospinal fluid (CSF)
Overview
Scio-Discover Pathway
Coverage Biomarker
Discovery Contact
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* Antibody array is designed to target human proteins. Due to a high sequence homology of vast majority of proteins it was often successfully applied to study murine, rat and ovine models as well [Thorenz A. et al. (2018), Peiro J. et al. (2018), Reichman H. et al. (2019), Raquel F. et al. (2020)].
** Depending on study design and sample numbers.