Our scioDiscover service enables high-content, immuno-based protein profiling of various biological samples leading to a comprehensive overview of proteomic changes. Key pathways in various diseases such as cancer, neurological disorders and organ failure are covered. The technology was successfully applied in a variety of biomedical studies and to discover new biomarker signatures. Within the analysis, 1,300 proteins are analysed in parallel. The scioDiscover protein array based service enables fast and targeted research while still offering a broad overview of potential changes on the protein level in your samples.
Features
- Major pathways, secreted proteins, cell surface and inflammatory markers are covered
- 1,300 proteins are profiled
- Broad spectrum of indications covered such as oncology and organ failure
- Robust dual-colour study design
- Including full data analysis and study report
- Studies possible in human, murine and rat samples*
Array
content Protein
profiling Biomarker
Discovery Target
Discovery Contact
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Advantages
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Which sample types can be analysed ?
With the scioDiscover service a variety of samples can be analysed:
- plasma / serum
- fresh frozen tissue samples
- cellular content
- cell culture supernatant
- cerebrospinal fluid
- additional sample types on request
- studies possible in samples from human, mouse or rat*
* Antibody array is designed to target human proteins. Due to a high sequence homology of vast majority of proteins it was often successfully applied to study murine, rat and ovine models as well [Thorenz A. et al. (2018), Peiro J. et al. (2018), Reichman H. et al. (2019), Raquel F. et al. (2020)].
Sample-to-result service
Within our analysis service, we will not only carry out the microarray experiments but also support you with a suggestion for an appropriate microarray study design as well as with the sample selection process in order to address your scientific question in the optimal way. Within 3-4 weeks after receipt of your samples you will receive a customised study report including a statistical analysis.
Our analysis service includes:
- definition of an appropriate study design
- sample preparation
- protein extraction
- protein concentration measurements
- protein quality control
- sample labelling
- sample purification
- incubation of the samples on antibody microarrays
- microarray scanning
- raw data acquisition
- data normalisation
- data analysis including cluster analysis
- statistical testing for differentially abundant proteins
- comprehensive study report
